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. 2011 Nov 30;6(11):e28376. doi: 10.1371/journal.pone.0028376

Figure 5. Effects of mifepristone and the Porsolt test on AMPA receptor expression in newborn cells.

Figure 5

A AMPA receptor expression in cells of different ages. AMPA receptor expression increased with age (p<0.001). B–J Images of double immunohistochemistry for the AMPA receptor (red) and IdU or CldU (green). The majority of 7 week-old cells were AMPA+. K Modulation of AMPA receptor expression by mifepristone. Mifepristone increased the proportion of AMPA+ cells in 1 week-old newborn cells (p = 0.003). ML: Molecular layer; GCL: Granule cell layer; SGZ: Subgranular zone; H: Hilus. Scale bar = 50 µm.