Table 1. Injection dates and doses of IdU and CldU (mg/Kg) administered to animals in each experimental group.
CldU | IdU | ||||
Date (Days) | Dosage (mg/Kg) | Date (Days) | Dosage (mg/Kg) | ||
GROUP A | −14, −13, −12, −11 | 57.65 | −28, −27, −26, −25 | 42.75 | |
GROUP B | −21, −20, −19, −18 | 57.65 | −7, −6, −5, −4 | 42.75 | |
GROUP C | −56, −55, −54, −53 | 57.65 | −42, −41, −40, −39 | 42.75 | |
GROUP D | −49, −48, −47, −36 | 57.65 | −7, −6, −5, −4 | 42.75 | |
GROUP E | - | - | - | - |
Group E animals received no injections and they were used to determine the hippocampal mRNA expression. Note that the doses were based on equimolar doses of 50 mg/kg BrdU. To avoid ethe ffects of the estrous cycle, animals received one injection of CldU or IdU on 4 successive days.