Table 2. Relative hippocampal mRNA expression (fold increase) in Group E animals.
| Control | Porsolt | |||
| Vehicle | Mifepristone | Vehicle | Mifepristone | |
| IL-6 | 1.24±0.14 | 1.22±0.27 | 1.23±0.24 | 1.41±0.24 |
| TNF | 0.97±0.08 | 1.15±0.25 | 0.80±0.13 | 1.22±0.32 |
| BDNF | 0.98±0.05 | 0.93±0.08 | 1.05±0.06 | 1.15±0.08 |
| IGF-I | 0.6±0.1 | 0.60±0.03 | 0.69±0.09 | 0.56±0.04 |
| vGLUT1 | 1.09±0.07 | 1.07±0.08 | 1.15±0.1 | 1.02±0.07 |
| GAD65 | 1.08±0.11 | 0.99±0.07 | 0.9±0.04 | 1.06±0.11 |
| GR | 1.06±0.06 | 0.98±0.07 | 1.05±0.12 | 0.98±0.1 |
| MR | 0.87±0.04 | 1.06±0.08 | 0.9±0.1 | 0.82±0.03 |
Neither the Porsolt test nor mifepristone administration significantly altered the mRNA expression of IL-6 (F3,18 = 0.777, p = 0.525), TNF (F3,15 = 1.331, p = 0.31), BDNF (F3,19 = 1.733, p = 0.201), IGF-I (F3,19 = 1.733, p = 0.201), vGLUT1 (F3,18 = 0.759, p = 0.31), GAD65 (F3,18 = 0.848, p = 0.489), GR (F3,18 = 1.654, p = 0.222), nor MR (F3,19 = 2.043, p = 0.148). Mouse GAPDH was used as an endogenous control. The data is presented as the relative increase (Pfaffl method). IL-6: Interleukin 6. TNF: Tumor necrosis factor. BDNF: Brain-derived neurotrophic factor. IGF-I: Insulin-like growth factor. vGLUT1: vesicular glutamate transporter 1. GAD65: Glutamic acid decarboxylase 65. GR: Glucocorticoid receptor. MR: Mineralocorticoid receptor.