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. 2001 Apr;12(4):931–942. doi: 10.1091/mbc.12.4.931

Figure 9.

Figure 9

Role of Y724 in full-length FGFR3. 293T cells transfected with full-length derivatives of FGFR3, with or without the Y724F mutation, were lysed and analyzed by immunoblotting. (A) Immunoblotting with antisera against FGFR3 shows equivalent expression levels of full-length FGFR3 derivatives. (B) Stat1 is phosphorylated in response to full-length constitutively active FGFR3 but not if the Y724F mutation is present. Lysates were examined by immunoblotting with anti-phospho-Stat1 (Y701) sera. Equal amounts of Stat1 were present in each sample.