Table 2.

Mean values of FA, MD, AxD and RD of major limbic tracts of AD patients and controls, standard deviation of these metrics of AD patients, t and p values (p^†) from tract level comparison and p (p^‡) value from tract group level comparison between AD and control are listed. Double asterisks and bold indicate statistically significant differences after FDR correction. The abbreviations for tables can be found in legend of Fig. 2.

Limbic Tracts
		FX-ST/L	FX-ST/R	FX-B	CGC-L	CGC-R	CGH-L	CGH-R
FA	AD	0.52	0.48	0.41	0.50	0.45	0.50	0.47
	Diff (AD-Ctr)	−0.052	−0.049	−0.085	−0.051	−0.040	−0.050	−0.039
	Std. Error	0.014	0.013	0.031	0.016	0.012	0.018	0.016
	T	−3.77	−3.60	−2.73	−3.21	−3.43	−2.84	−2.51
	p†	<0.001**	0.001**	0.01**	0.003**	0.002**	0.008**	0.02**
	Tract group p‡	<0.001**
MD (10−3mm2/S)	AD	0.79	0.80	0.97	0.76	0.79	0.70	0.69
	Diff (AD-Ctr)	0.044	0.025	0.15	0.027	0.045	0.043	0.011
	Std. Error	0.014	0.023	0.061	0.011	0.021	0.017	0.013
	T	3.17	1.12	2.55	2.59	2.10	2.58	0.86
	p†	0.003**	0.27	0.02**	0.01**	0.04**	0.01**	0.4
	Tract group p‡	0.007**
AxD (10−3mm2/S)	AD	1.26	1.23	1.60	1.24	1.20	1.12	1.06
	Diff (AD-Ctr)	−0.012	−0.036	−0.081	−0.019	0.021	−0.019	−0.035
	Std. Error	0.011	0.026	0.051	0.021	0.016	0.013	0.023
	T	−0.52	−1.37	−1.24	−0.78	0.73	−0.64	−1.48
	p†	0.61	0.18	0.22	0.44	0.47	0.52	0.15
	Tract group p‡	0.19
RD (10−3mm2/S)	AD	0.54	0.58	0.66	0.53	0.58	0.50	0.51
	Diff (AD-Ctr)	0.071	0.052	0.057	0.056	0.062	0.071	0.040
	Std. Error	0.017	0.023	0.021	0.015	0.021	0.023	0.015
	T	4.24	2.24	2.65	3.64	2.90	3.09	2.74
	p†	<0.001**	0.03**	0.01**	<0.001**	0.007**	0.004**	0.01**
	Tract group p‡	0.002**