Table 5.
Mean values of FA, MD, AxD and RD of major projection tracts of AD patients and controls, standard deviation of these metrics of AD patients, t and p values (p†) from tract level comparison and p (p‡) value from tract group level comparison between AD and control are listed. Double asterisks and bold indicate statistically significant differences after FDR correction. The abbreviations for tables can be found in legend of Fig. 2.
Projection Tracts | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
ACR-L | ACR-R | PCR-L | PCR-R | SCR-L | SCR-R | ALIC-L | ALIC-R | PLIC-L | PLIC-R | ||
FA | AD | 0.42 | 0.40 | 0.50 | 0.48 | 0.48 | 0.46 | 0.56 | 0.58 | 0.69 | 0.72 |
Diff (AD-Ctr) | −0.011 | −0.028 | 0.009 | 0.007 | 0.006 | 0.002 | 0.003 | 0.007 | 0.008 | 0.022 | |
Std. Error | 0.010 | 0.011 | 0.008 | 0.005 | 0.005 | 0.002 | 0.002 | 0.006 | 0.005 | 0.014 | |
t | −1.01 | −2.63 | 0.83 | 0.58 | 0.56 | 0.22 | 0.34 | 0.60 | 0.71 | 1.54 | |
p† | 0.32 | 0.013** | 0.41 | 0.57 | 0.58 | 0.82 | 0.73 | 0.55 | 0.48 | 0.13 | |
Tract group p‡ | 0.50 | ||||||||||
MD (10− 3mm2 /S) |
AD | 0.79 | 0.80 | 0.78 | 0.78 | 0.75 | 0.75 | 0.73 | 0.73 | 0.68 | 0.65 |
Diff (AD-Ctr) | 0.043 | 0.051 | 0.37 | 0.033 | 0.042 | 0.030 | 0.026 | 0.014 | 0.009 | −0.014 | |
Std. Error | 0.016 | 0.016 | 0.019 | 0.016 | 0.015 | 0.013 | 0.012 | 0.011 | 0.008 | 0.011 | |
T | 2.73 | 3.14 | 1.96 | 2.09 | 2.80 | 2.41 | 2.27 | 0.96 | 1.07 | −1.09 | |
p† | 0.010** | 0.003** | 0.058 | 0.043** | 0.008** | 0.022** | 0.029** | 0.34 | 0.30 | 0.28 | |
Tract group p‡ | 0.017** | ||||||||||
AxD (10− 3mm2 /S) |
AD | 1.18 | 1.17 | 1.25 | 1.22 | 1.19 | 1.17 | 1.25 | 1.27 | 1.34 | 1.31 |
Diff (AD-Ctr) | 0.054 | 0.041 | 0.068 | 0.059 | 0.078 | 0.054 | 0.051 | 0.032 | 0.031 | 0.002 | |
Std. Error | 0.017 | 0.018 | 0.027 | 0.018 | 0.027 | 0.021 | 0.018 | 0.016 | 0.011 | 0.001 | |
T | 3.15 | 2.22 | 2.49 | 3.27 | 2.95 | 2.61 | 2.81 | 1.34 | 1.38 | 0.09 | |
p† | 0.003** | 0.033** | 0.018** | 0.003** | 0.006** | 0.013** | 0.008** | 0.19 | 0.18 | 0.93 | |
Tract group p‡ | 0.017** | ||||||||||
RD (10− 3mm2 /S) |
AD | 0.60 | 0.61 | 0.54 | 0.55 | 0.53 | 0.54 | 0.47 | 0.46 | 0.35 | 0.33 |
Diff (AD-Ctr) | 0.038 | 0.056 | 0.023 | 0.019 | 0.027 | 0.018 | 0.013 | 0.057 | −0.001 | −0.019 | |
Std. Error | 0.016 | 0.017 | 0.011 | 0.011 | 0.017 | 0.012 | 0.011 | 0.013 | 0.001 | 0.014 | |
T | 2.33 | 3.28 | 1.25 | 1.10 | 1.92 | 1.52 | 1.09 | 0.43 | −0.11 | −1.33 | |
p† | 0.025** | 0.002** | 0.22 | 0.28 | 0.064 | 0.14 | 0.28 | 0.67 | 0.91 | 0.19 | |
Tract group p‡ | 0.062 |