Table 1.
Prevalence of traditional cardiovascular risk factors and biologic measurements in women with SLE and female controls
| Controls (n=65) |
SLEs (n=121) |
P* | |
|---|---|---|---|
| Demographics | |||
| Age (years) | 41 (32–46) | 39 (30–46) | 0.470 |
| Caucasian (%) | 48 (74%) | 81 (67%) | 0.330 |
| Disease duration (years) | NA | 6.0 (3.0–11.0) | --- |
| Lipid profile | |||
| Total cholesterol (mg/dL) | 184 (161–206) | 163 (138–203) | 0.031 |
| High-density lipoprotein cholesterol (mg/dL) | 47 (40–61) | 49 (37–56) | 0.776 |
| Low-density lipoprotein cholesterol (mg/dL) | 112 (89–137) | 92 (76–124) | 0.005 |
| Triglycerides (mg/dL) | 77 (61–108) | 96 (71–146) | 0.008 |
| Current use of statins | 5 (8%) | 10 (8%) | 0.879 |
| Other cardiovascular risk factors | |||
| Systolic blood pressure (mmHg) | 114 (106–127) | 115 (106–124) | 0.724 |
| Diastolic blood pressure (mmHg) | 70.0 (65.0–78.0) | 71.5 (65.0–78.5) | 0.606 |
| Body mass index (kg/m2) | 24.9 (22.0–30.3) | 26.6 (23.2–32.5) | 0.110 |
| Use of anti-hypertensive drugs | 7 (11%) | 37 (31%) | 0.002 |
| Current smoking status | 11 (17%) | 25 (21%) | 0.538 |
| Family history of coronary heart disease | 9 (14%) | 21 (17%) | 0.535 |
| C-reactive protein (mg/L) | 0.57 (0.17–2.48) | 3.00 (0.68–6.00) | <0.001 |
| Presence of subclinical atherosclerosis¶ | 4 (6%) | 21 (17%) | 0.033 |
Data are presented as median (interquartile range) for continuous variables, count (percentage) for categorical variables.
¶
Subclinical atherosclerosis present if coronary artery calcium >0 Agatston units
*
Wilcoxon’s rank sum test was used for comparing continuous variables, and percentages were compared using the chi-square test.