Table 1.
Status Of LPO, SOD and CAT in mucosa before and after treatment with antioxidants
| Group | LPO (nmol/mg protein) | SOD (U/g wet tissue) | CAT (U/g wet tissue) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Before Rx | After Rx | P value | Before Rx | After Rx | P value | Before Rx | After Rx | P value | |
| A(10) | 0193 ± 0.444 | 0.170 ± 0.03 | 40.3 ± 6.1 | 39.0 ± 5.3 | 62.3 ± 7.2 | 64.8 ± 7.88 | |||
| BI(10) | 0.219 ± 0.049 | 0.175 ± 0.043 | <0.01 | 51.4 ± 6.4 | 34.9 ± 3.7 | <0.01 | 37.7 ± 8.0* | 53.5 ± 8.7 | <0.001 |
| BII(14) | 0.316 ± 0.048 | 0.268 ± 0.046 | <0.001 | 50.2 ± 4.0 | 34.3 ± 3.9 | <0.001 | 48.8 ± 8.0 | 66.1 ± 8.7 | <0.001 |
| BIII(7) | 0.289 ± 0.031 | 0.239 ± 0.024 | <0.01 | 50.6 ± 4.7 | 33.8 ± 2.4 | <0.01 | 43.4 ± 5.0 | 79.9 ± 6.5 | <0.001 |
Note: Statistical analysis was done by paired t test
Results in Mean + SEM (standard error of mean)
Group A: control group i.e. having no leukoplakia—10 healthy individuals; Group BI: leukoplakia with no dysplasia—10 patients; Group BII: Leukoplakia with mild dysplasia—14 patients; Group BIII: Leukoplakia with moderate dysplasia—7 patients
LPO lipid peroxidase, SOD superoxide dismutase, CAT catalase, Rx Treatment
* P value < 0.05