Table 2.
Status of LPO, SOD and CAT in serum before and after treatment with antioxidants
| Group | LPO (nmol/mg protein) | SOD (U/g wet tissue) | CAT (U/g wet tissue) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Before Rx | After Rx | P value | Before Rx | After Rx | P value | Before Rx | After Rx | P value | |
| A(10) | 0.371 ± 0.079 | 0.034 ± 0.081 | 49.3 ± 1.99 | 48.8 ± 1.92 | 174.4 ± 16.3 | 183.2 ± 17.8 | |||
| BI(10) | 0.532 ± 0.110 | 0.436 ± 0.102 | <0.001 | 65.3 ± 2.78*** | 50.6 ± 2.10 | <0.001 | 120.1 ± 13.6* | 144.3 ± 17.7 | <0.001 |
| BII(14) | 0.628 ± 0.070* | 0.560 ± 0.072 | <0.001 | 60.5 ± 2.48** | 54.9 ± 1.40 | <0.001 | 141.6 ± 21.1 | 180.9 ± 20.7 | <0.001 |
| BIII(7) | 0.468 ± 0.024 | 0.396 ± 0.024 | <0.05 | 71.7 ± 2.30*** | 52.2 ± 1.8 | <0.001 | 130.2 ± 24.1 | 173.7 ± 26.4 | <0.001 |
Note: Statistical analysis was done by paired t test
Results in Mean + SEM (standard error of mean)
Group A: control group i.e. having no leukoplakia—10 healthy individuals; Group BI: leukoplakia with no dysplasia—13 patients; Group BII: Leukoplakia with mild dysplasia—11 patients, Group BIII: Leukoplakia with moderate dysplasia—7 patients
LPO lipid peroxidase, SOD superoxide dismutase, CAT catalase, Rx Treatment
* P value < 0.05
** P value < 0.01
*** P value < 0.001