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Comparing principles underlying the use of combined cytotoxic agents versus combining targeted agents
Abbreviations: CML, chronic myelogenous leukemia; MTA, molecularly targeted agent; PD, pharmacodynamic; PK, pharmacokinetic.
Adapted from Takimoto CH, Calvo E. Chapter 3: Principles of oncologic pharmacotherapy. In: Pazdur R, Coia L, Hoskins WJ et al., eds. Cancer Management: A Multidisciplinary Approach, Ninth Edition. Lawrence, KS: CMP Healthcare Media LLC, 2005:23–42.
