Table 3.

Treatment regimens and dose intensity

^aThe number of cycles received was reported as “5 or more” for most patients. It was assumed that the median number of cycles received was equal to 6.

^bInitial planned doses of gemcitabine and carboplatin for level 3 were, respectively, 1,200 mg/m² and 5 AUC mg-min/ml, but were amended to 1,000 mg/m² and 4 AUC mg-min/ml, as a result of toxicity.

^cProportion of doses.

^dProportion of patients.

Abbreviations: AUC, area under the curve; PLD, pegylated liposomal doxorubicin.