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. 2010 Oct 7;15(10):1073–1082. doi: 10.1634/theoncologist.2009-0331

Table 5B.

Grade III and IV nonhematological toxicities (% of patients)

graphic file with name onc01010-0668-t06.jpg

aWhen nausea and vomiting were reported separately, the maximum number is shown.

bOnly nausea was reported.

cReported as nausea/emesis.

dReported as infection with neutropenia.

eReported as infection from grade III or IV neutropenia.

fReported as infection with neutropenia (infection without neutropenia, 0% and 0.6% for grade III and IV, respectively).

gReported as neuropathy.

hNumbers for neuropathy are the maximum between motor and sensory neuropathy.

iReported as neurotoxicity.

jReported as peripheral neuropathy.

kReported as fatigue/malaise/lethargy.

lReported as abdominal pain/cramping.

mReported as abdominal pain.

nReported as palmar–plantar erythrodysesthesia.

Abbreviations: HFS, hand–foot syndrome; NA, not available; PLD, pegylated liposomal doxorubicin.