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Recommended zoledronic acid and ibandronate dose reductions in patients with decreased renal function
aDoses calculated to achieve an area under the curve of 0.66 mg-h/ml with a creatinine clearance of 75 ml/min (using Cockcroft-Gault formula). Data from zoledronic acid prescribing information [78].
bAdministration every 3 to 4 weeks. Data from ibandronate summary of product characteristics [80].
Abbreviations: ZOL, zoledronic acid; IBN, ibandronate.
