Pathologic complete response (pCR) rate according to alkylating agent dose. (A): Patients with p53-mutated tumors. (B): Patients with wild-type p53 tumors.
Abbreviations: ddEC, dose-dense epirubicin and cyclophosphamide; E, single-agent epirubicin; FAC, 5-fluorouracil, doxorubicin, and cyclophosphamide.