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Radiation induced EGFR and TGF-α mRNA expression and cetuximab inhibited it. At day corresponding to A431 cell implantation, quantification of mRNA was performed as described in Materials and Methods. Values are the mean ± standard error of three independent experiments with two replicates per experiment.
*p < .05 (Mann-Whitney test).
Abbreviations: EGFR, epidermal growth factor receptor; TGF-α, transforming growth factor α; XRT, radiation.
