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. 2011 Jan 6;16(1):5–24. doi: 10.1634/theoncologist.2010-0190

Table 2.

Recent phase III trials in patients with metastatic melanoma

graphic file with name onc00111-0733-t05.jpg

aDisease stage by AJCC/UICC criteria.

bRequired, planned number of patients.

cThis study was halted for safety reasons by an independent Data Monitoring Committee; there was also an imbalance in the outcome of patients treated in the different cohorts.

Abbreviations: AJCC, American Joint Committee on Cancer; DTIC, dacarbazine; EORTC, European Organization for Research and Treatment of Cancer; IL, interleukin; LDH, lactate dehydrogenase; OS, overall survival; PFS, progression-free survival; TTP, time to progression; UICC, International Union Against Cancer.