Figure 3.

Kaplan–Meier estimates of PFS. PFS on first-line systemic therapy (blue), second-line systemic therapy (orange), and phase I therapy (red). The median PFS time on first-line treatment was significantly longer than the median PFS time on phase I treatment (p < .0001). The median PFS time on second-line treatment was longer than the median PFS time on phase I treatment and at borderline statistical significance (p = .05).

Abbreviations: CI, confidence interval; PFS, progression-free survival.