Table 2.

Clinical pharmacogenetics of dihydropyrimidine dehydrogenase (DPYD)

^aAdapted from http://www.cancer.gov. See also Table 1.

Abbreviations: 5-FU, 5-fluorouracil; CRC, colorectal cancer; GI, gastrointestinal; HET, heterozygous mutant patients; NA, not analyzed; SNP, single nucleotide polymorphism; UP, unknown primary.