Fig. (2).

Skin prick reactions by freshly obtained self-saliva, filter-sterilized self-saliva, and control saline. (A) In a 27 year-old male BD patient with active aphthous ulceration (case #4, Table 1), an intense and indurative erythema with a small pustule was established by a skin prick with neat self-saliva (S, left), but showed a tiny dot reaction by filter-sterilized self-saliva (SS, middle). A skin prick with control saline did not cause any of skin reactions (CS, right). (B) In a 26 year-old female BD patient without aphthous ulceration (case #3, Table 1), a very mild erythema but central pustules were established by a skin prick with neat (S, left) and filter-sterilized self-saliva (SS, middle), and even by control saline (CS, right).