Table 4.
Summary of the mean time to onset of complications
| Time to onset of complications (years) |
|||
|---|---|---|---|
| Complication | Lispro | Regular insulin | Difference |
| Any complications | 0.45 | 0.43 | 0.02 |
| Background retinopathy | 3.01 | 2.86 | 0.15 |
| Proliferative retinopathy | 12.24 | 12.05 | 0.19 |
| Microalbuminuria | 5.02 | 4.93 | 0.09 |
| Gross proteinuria | 8.27 | 8.08 | 0.19 |
| End-stage renal disease | 15.69 | 15.58 | 0.11 |
| First event ulcer | 13.63 | 13.49 | 0.14 |
| Amputation | 16.26 | 16.13 | 0.13 |
| Neuropathy | 3.46 | 3.34 | 0.12 |
| Peripheral vascular disease | 15.98 | 15.83 | 0.15 |
| Congestive heart failure | 15.98 | 15.87 | 0.11 |
| Angina | 16.44 | 16.36 | 0.08 |
| Myocardial infarction | 15.92 | 15.78 | 0.14 |
| Stroke | 16.79 | 16.68 | 0.11 |
| Cataract | 15.99 | 15.88 | 0.11 |
| Macular oedema | 12.79 | 12.62 | 0.17 |
| Severe vision loss | 14.60 | 14.47 | 0.13 |
Time to onset of diabetes-related complications of the base-case.
Values expressed are means.