Table 2.

HLA-B expression following in vitro treatment with IFN-γ or LPS^*

Treatment	Patient (mean, 95% CI)	Control (mean, 95% CI)
No stimulation	559 (356, 875)	770 (492, 1204)
LPS 10 ng/mL	664 (413, 1065)	1551 (969, 2479)
LPS 100 ng/mL	596 (380, 933)	855 (546, 1336)
IFN-γ	1249 (799, 1949)	1239 (793, 1933)
IFN-γ+LPS 10 ng/mL	1071 (668, 1713)	1911 (1195, 3052)
IFN-γ+LPS 100 ng/mL	1375 (881, 2145)	1577 (1010, 2459)

^*Means were derived from log transformed expression values (see Methods). Patients did not respond differently than controls to treatment (p=0.119). The only significant effect was by IFN-γ treatment, which increased the response for all treatments (IFN-γ only or IFN-γ+LPS) for both patients and controls (p<0.0001). N=7–8 AS patients and controls per group.