Table 2.

N/M ratio measurements of intimal proliferation

Treatment	High dose (1 mg/kg)	Low dose (0.3 mg/kg)
Sham, injury only (saline)	1.249 ± 0.046	—
Paclitaxel	0.837 ± 0.087†	0.937 ± 0.126*
NP	0.749 ± 0.136†	1.063 ± 0.097
Nanoburrs	0.662 ± 0.169†	0.744 ± 0.129†,‡

N/M ratios taken from the site of greatest luminal narrowing per artery. Doses indicate active paclitaxel drug composition. Animals were dosed on days 0 and 5 postsurgery and the study was concluded on day 14. All results are expressed as mean ± SEM, n = 5. *P < 0.05 versus injury only; ^†P < 0.01 versus sham, injury-only; ^‡P = 0.08 versus NP, by one-way ANOVA with Tukey's post hoc test.