Table 1.

Numbers of Created In Vivo Binding Sites and Corresponding Creation Efficiencies

Factor	d+	d−	Nond+	Nond−	CEdeam	CEnondeam	CEdeam/CEnondeam	P value	% of d+
c-Myc_canonical	5	187	13	4050	0.026042	0.003200	8.0	9.4E−4	27.8
c-Myc_noncanonical	26	976	21	11706	0.025948	0.001791	14.5	3.4E−17	55.3
Ctcf	90	3356	832	199548	0.026117	0.004152	6.3	5.2E−40	9.8
Irf4	24	769	327	136133	0.030265	0.002396	12.6	1.9E−18	6.8
Nanog	70	972	246	91794	0.067178	0.002672	25.1	2.2E−111	22.2
Nfya	21	1207	50	27906	0.017101	0.001788	9.6	7.1E−13	29.6
Nfyb	22	1417	70	34235	0.015288	0.002041	7.5	9.4E−12	23.9
Nrsf	5	195	10	4207	0.025000	0.002371	10.5	3.5E−4	33.3
OCT4	33	382	99	24123	0.079518	0.004039	19.7	2.4E−29	25.0
Pax5	83	9321	244	146697	0.008826	0.001661	5.3	1.4E−29	25.4
Pbx3	10	609	35	15217	0.016155	0.002294	7.0	6.1E−6	22.2
Rxra	26	1299	83	55298	0.019622	0.001498	13.1	4.0E−19	23.8
Usf1	52	506	272	17701	0.093190	0.015134	6.2	2.1E−23	16.0
YY1	8	1354	27	19203	0.005874	0.001404	4.2	1.3E−3	22.9

NOTE.—The following values are listed: the numbers of observed new site creations due to CpG deamination events (d+) and nondeamination events (nond+); the numbers of potential deamination and nondeamination-driven creation events which could lead to site creation but have not been observed (d− and nond−, respectively); creation efficiencies for deamination-driven creation events (CE_deam), nondeamination-driven creation events (CE_nondeam), and percentages of deamination-driven creation events (% of d+). The P value was calculated with Fisher’s exact test.