Table 2.

Pubmed/Medline search strategy

(((((“open fracture”[tw] OR “open fractures”[tw]) OR (“Fractures, Open”[Mesh]) OR (“complex fractures”[tw] OR “complex fracture”[tw]) OR (“compound fracture”[tw] OR “compound fractures”[tw])) AND ((ankle[tw] OR ankles[tw]) OR (“Ankle”[Mesh]))) OR (((“Fractures, Bone”[Mesh:noexp]) OR (“bone fracture”[tw] OR “bone fractures”[tw])) AND (open[tw]) AND ((ankle[tw] OR ankles[tw]) OR (“Ankle”[Mesh]))) OR (((“malleolar fracture”[tw] OR “malleolar fractures”[tw]) OR (“ankle fracture”[tw] OR “ankle fractures”[tw])) AND (open[tw]))) AND ((“Treatment Failure”[Mesh]) OR (treatment[tw]) OR (“operative procedure”[tw] OR “operative procedures”[tw]) OR (“Surgical Procedures, Operative”[Mesh:noexp]) OR (“debridement”[MeSH Terms] OR “debridement”[tw]) OR (“Irrigation”[Mesh:noexp]) OR (Irrigation[tw]) OR (lavage[tw]) OR (“Anti-Bacterial Agents”[Mesh:noexp]) OR (antibiotics[tw]) OR (“Fracture Fixation, Internal”[Mesh]) OR (“internal fracture fixation”[tw]) OR (osteosynthesis[tw])))