Table 3. Relation of Moderate-to-Very Severe CAA to Five Cognitive Domains and Global Cognition.
Cognitive Score | Estimatea (SE), p |
---|---|
Perceptual speed | −0.50 (0.20), 0.012 |
Episodic memory | −0.46 (0.23), 0.047 |
Semantic memory | −0.21 (0.22), 0.340 |
Working memory | 0.03 (0.16), 0.865 |
Visuospatial abilities | −0.27 (0.17), 0.102 |
Global cognition | −0.35 (0.19), 0.066 |
Model terms include CAA class variable predictors for moderate-to-very severe CAA (shown), mild-to-moderate CAA, and terms adjusting for age-at-death, sex, education, AD pathology, cerebral infarcts, and Lewy bodies.
β-Coefficient.
AD = Alzheimer disease; CAA = cerebral amyloid angiopathy; SE = standard error.