. 2011 Dec 1;6(12):e27751. doi: 10.1371/journal.pone.0027751

Table 3. A comparative summary of IN-DNA S-S crosslinking with mixed disulfide–modified substrates.

`Substrate`	`L4-3`	`L4-10`	`L4-12`	`L3-2`	`Y3-2`	`L3-12`	`Y3-12`	`L4-3 processed`
`Cys position`
`146`	`++`				`+`	`+/−`
`146, 244`	`+/−`	`+/−`	`++`	`++`	`++`
`244`	`+/−`	`+/−`				`+d*`	`++d*`
`125`	`+`			`+`	`+`
`125, 157`	`++`		`+/−`		`+`	`+`		`++`

The efficiency of crosslinking is shown by a number of (+) signs. The most efficient contact sites are shown in bold (++). The DNA substrates used are shown in the top row; d* indicates preference for dimer formation. Linear(L) and Y-mer(Y) dsDNA substrates with thiol groups introduced in the bases of certain strand (e.g. L4 carries a modification in strand 4 (processed strand of viral end) at certain position (e.g. L3-12 is modified at 12^th nucleotide from 5′-end of the non-processed strand, or L4-3 – at 3^rd position (A) of processed strand that is next to scissile phosphate.