Table 1.
Clinical Characteristics of Study Subjects
| Non-AS (n = 79) | AS (n = 41) | |
|---|---|---|
| Demographics | ||
| Mean age, years | 65 ± 12 | 72 ± 12* |
| Female gender, % | 11 | 34* |
| Height, cm | 165 ± 8 | 157 ± 9* |
| Body weight, kg | 65 ± 12 | 58 ± 10* |
| Systolic blood pressure, mmHg | 129 ± 21 | 137 ± 28 |
| Heart rate, beats/min | 67 ± 12 | 69 ± 14 |
| Medical history | ||
| Hypertension, % | 70 | 78 |
| Diabetes mellitus, % | 34 | 39 |
| Dyslipidemia, % | 67 | 71 |
| Current smoking, % | 46 | 20* |
| Coronary artery disease, % | 73 | 85 |
| Chronic kidney disease, % | 41 | 76* |
| Medication use | ||
| Beta blocker, % | 27 | 29 |
| Calcium channel blocker, % | 39 | 44 |
| ACEI/ARB, % | 56 | 66 |
| Diuretics, % | 20 | 20 |
| Statin, % | 46 | 46 |
| Measurements | ||
| eGFR, ml/min/1.73 m2 | 64 ± 23 | 53 ± 18* |
| Hemoglobin, g/dl | 13.2 ± 2.0 | 12.8 ± 1.9 |
| Calcium, mg/dl | 9.4 ± 0.6 | 9.5 ± 0.6 |
| Phosphate, mg/dl | 3.4 ± 0.6 | 3.4 ± 0.6 |
| Total cholesterol, mg/dl | 185 ± 44 | 182 ± 30 |
| HDL-cholesterol, mg/dl | 50 ± 18 | 50 ± 14 |
| LDL-cholesterol, mg/dl | 108 ± 36 | 105 ± 24 |
| Triglyceride, mg/dl | 135 ± 64 | 131 ± 55 |
| Hemoglobin A1C, % | 6.0 ± 1.0 | 6.1 ± 0.8 |
| C-reactive protein, mg/dl | 0.20 ± 0.28 | 0.32 ± 0.79 |
AS: aortic stenosis; ACEI: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor blocker; eGFR: estimated glomerular filtration rate; HDL: high density lipoprotein; LDL: low density lipoprotein. *P < 0.05 versus non-AS.