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Effect of benzothiazole based compounds on microRNAs miR-195a, miR-101-1. The HepG2 cells were treated with compounds A3 and A4 at 4 μM concentration. Total RNA was isolated and the RNA was poly A tailed using Poly A polymerase and were subjected micro RNA specific RT-PCR study. Equal mRNA was used for the study. Each experiment was repeated three times. The results obtained were from three independent experiments and are statistically significant at p < 0.001 for compound A4.
