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Effect of benzothiazole based compounds in the activation of Caspase-3 and PARP. HepG2 cells were treated with compounds YM, A3 and A4 for 24 h. The total cell lysates were harvested and analysed by immunoblotting with antibodies against active caspase-3 and cleaved PARP. YM is the positive control. β-actin was used as loading control. The results obtained were from three independent experiments and are statistically significant at p < 0.001 for compound A4.
