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. 2011 Dec 1;7(12):e1002385. doi: 10.1371/journal.ppat.1002385

Figure 11. Model of the cAMP/PKA signaling pathway in M. oryzae.

Figure 11

In this model, the rice blast fungus responds to external physical cues from the rice leaf surface that are detected by receptors such as Pth11 and are transmitted via the heterotrimeric G-protein leading to Mac1 adenylate cyclase activation. This activates the cyclic AMP dependent protein kinase A, CpkA, which in turn acts upstream of MoSom1, a transcriptional regulator that acts through a set of transcription factors including MoStu1, MoCdtf1 and others to bring about infection-assocaited development.