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The temporal pattern of illness recurrence in patients with neurosyphilis artificially infected for malaria therapy with Plasmodium falciparum (87 patients) and the "Madagascar" strain of P. vivax (105 patients) studied by SP James and colleagues at the Horton Hospital, Epsom, England [24-26]between 1925 and 1930. The vivax relapses had a bimodal pattern with the majority having a long latent period (mode 28 weeks) before the relapse.
