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Expression of PROK1 and PROKR1 mRNA in human uteroplacental tissues at term. PROK1 mRNA expression is elevated in myometrium and placenta during labor at term compared with the tissues collected at term before the onset of labor (A). Levels of PROKR1 mRNA do not vary with the onset of labor; however, notably, PROKR1 levels are highest in myometrium compared with other uteroplacental tissues (B). Results are presented as mean ± SEM. *P < 0.05, **P < 0.0001 (n = 10 to 12).
