Table 1.

Cross-sectional study results for MPA-treated and matched control macaques

	Duration of MPA (mo)	No. of control macaquesa	Age (y)		Weight (kg)		Basal glucose (mg/dL)		Basal insulin (µU/mL)		Insulin sensitivity (×10–4)
Macaque			MPA	control	MPA	control	MPA	control	MPA	control	MPA	control
C1	1.4	6	22.2	22.4	7.05	8.11	73	62	15	36	2.40	3.90
C2	8.0	4	12.3	12.5	11.85	11.25	58	60	80	53	0.61	2.86
C3	8.1	5	15.6	15.3	12.71	11.00	60	65	93	67	0.73	3.59
C4	10.5	5	14.3	14.1	6.18	6.49	56	60	28	24	2.20	9.30
C5	31.1	8	20.3	20.2	10.21	10.31	50	62	86	79	2.53	3.95
C6	36.1	6	21.3	21.3	9.66	10.19	43	79	45	92	0.25	3.94
Pb			0.57		0.89		0.28		0.96		0.02

^aNumber of healthy age- and weight-matched macaques that were used to calculate means for comparison.

^bP value from paired t test of each study subject compared with age- and weight-matched healthy macaque (n = 4 to 8 animals per study subject). Statistical significance was defined as P < 0.05.