Table 1.
Anatomic, echocardiographic and hemodynamic data
| Sham | MI | |
|---|---|---|
| Anatomic data | (n = 20) | (n = 24) |
| Body weight (kg) | 30 ± 1 | 32 ± 1 |
| RVW/BW (g/kg) | 0.99 ± 0.05 | 1.35 ± 0.06*** |
| LVW/BW (g/kg) | 2.87 ± 0.09 | 3.38 ± 0.06*** |
| Echocardiographic data | (n = 9) | (n = 13) |
| LV EDA (mm2) | 921 ± 47 | 1,551 ± 157** |
| LV ESA (mm2) | 306 ± 34 | 985 ± 128*** |
| 2D-ejection fraction (%) | 67 ± 3 | 37 ± 3*** |
| Hemodynamic data | (n = 18) | (n = 20) |
| MAP (mm Hg) | 93 ± 5 | 94 ± 4 |
| Heart rate (bpm) | 115 ± 4 | 116 ± 7 |
| Cardiac output (l/min) | 3.4 ± 0.2 | 3.3 ± 0.2 |
| Stroke volume (ml) | 30 ± 2 | 30 ± 2 |
| LV dP/dtP40 (mm Hg/s) | 1743 ± 88 | 1,411 ± 51** |
| Tau (ms) | 36 ± 2 | 43 ± 2* |
| LV EDP (mm Hg) | 7.7 ± 0.8 | 13.0 ± 1.4** |
Values are mean ± SEM
BW body weight, RVW and LVW, right and left ventricle weight, EDA and ESA end-diastolic and end-systolic cross-sectional area, MAP mean aortic pressure, LV dP/dt P40 rate of rise in LV pressure at 40 mm Hg, EDP end-diastolic pressure
* p < 0.05; ** p < 0.01; *** p < 0.001 versus sham