Table 2.
Genotype frequencies of six SNPs in the CR1 gene in control subjects and three groups of infected subjects (P. falciparum, P. vivax and P.falciparum + P. vivax).
| Controls (n = 27) | P. falciparum (n = 25) | p | P. vivax (n = 34) | p | P. falciparum + P. vivax (n = 33) | p | ||
|---|---|---|---|---|---|---|---|---|
| CR1-4646 A > G | A/A | 18 (66.6%) | 21 (84%) | 28 (82.3%) | 27 (81.8%) | |||
| N1540S | A/G | 7 (25%) | 4 (16%) | 6 (17.7%) | 6 (18.2%) | |||
| G/G | 2 (7.4%) | 0 (0%) | 0 (0%) | 0 (0%) | ||||
| - | - | - | ||||||
| CR1-4708 G > A | G/G | 26 (93.3%) | 18 (72%) | 28 (82.3%) | 26 (78.8%) | |||
| V1561M | G/A | 1 (3.7%) | 7 (28%) | 6 (17.7%) | 7 (21.2%) | |||
| Kna/b | A/A | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| 0.0216 | 0.1207 | 0.063 | ||||||
| CR1-4795 A > G | A/A | 25 (92.6%) | 21 (84%) | 31 (91.2%) | 31 (93.9%) | |||
| K1590E | A/G | 2 (7.4%) | 4 (16%) | 2 (5.9%) | 2 (6.1%) | |||
| McCa/b | G/G | 0 (0%) | 0 (0%) | 1 (2.9%) | 0 (0%) | |||
| - | - | - | ||||||
| CR1-4828 A > G | A/A | 20 (74.1%) | 17 (68%) | 30 (88.2%) | 23 (69.7%) | |||
| R1601G | A/G | 7 (25.9%) | 8 (32%) | 3 (8.8%) | 9 (27.3%) | |||
| Sl1/Sl2 | G/G | 0 (0%) | 0 (0%) | 1 (3%) | 1 (3%) | |||
| 0.630 | 0.319 | 0.563 | ||||||
| CR1-4855 T > A | T/T | 27 (100%) | 25 (100%) | 34 (100%) | 33 (100%) | |||
| S1610T | T/A | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| Sl4/Sl5 | A/A | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| __ | __ | __ | ||||||
| CR1-4870 A > G | A/A | 10 (37%) | 5 (20%) | 12 (35.3%) | 12 (36.4%) | |||
| I1615V | A/G | 11 (40.7%) | 15 (60%) | 14 (41.2%) | 12 (36.4%) | |||
| KAM−/KAM+ | G/G | 6 (22.3%) | 5 (20%) | 8 (23.5%) | 9 (27.2%) | |||
| 0.448 | 0.876 | 0.776 | ||||||