Carriers                 Non-carriers                                                                       (n= 29)                    (n=43)                                                           RoC                         RoC                      P              ph2
Motor b
UHDRS TMS	0.217 (1.440)	-0.475 (0.639)	.024*	.083
Eye movement	-0.037 (0.401)	-0.141 (0.294)	.431	.011
Voluntary movement	0.012 (0.375)	-0.149 (0.252)	.103	.045
Chorea	0.235 (0.523)	-0.052 (0.328)	.008**	.114
Behavioural b
UHDRS TBS	0.164 (2.178)	0.380 (1.485)	.634	.003
Sadness	0.025 (0.581)	0.093 (0.313)	.634	.003
Anxiety	0.079 (0.556)	0.043 (0.326)	.554	.005
Aggression	0.019 (0.457)	0.084 (0.321)	.388	.011
Irritability	0.039 (0.493)	0.091 (0.375)	.401	.010
Neuropsychological
MMSE, total score	0.012 (0.213)	0.057 (0.200)	.319	.014
WAIS-R Information	0.030 (0.236)	0.007 (0.129)	.706	.002
Digit span	0.048 (0.260)	0.057 (0.225)	.994	.000
Arithmetic	-0.006 (0.321)	0.016 (0.296)	.728	.002
Picture arrangement	0.067 (0.255)	0.004 (0.314)	.745	.002
Block design	-0.028 (0.314)	0.035 (0.228)	.156	.029
WMS, memory quotient	-0.265 (1.813)	0.760 (1.593)	.015*	.084
Concentration	-0.134 (0.236)	0.004 (0.148)	.007**	.101
Logical memory	-0.170 (0.369)	-0.015 (0.298)	.065	.049
Visual reproduction	-0.129 (0.327)	0.008 (0.313)	.045*	.057
Associative learning	-0.119 (0.330)	-0.046 (0.368)	.656	.003
Verbal fluency (FAS)	0.187 (1.181)	0.428 (1.131)	.174	.027
Boston naming test	0.074 (0.193)	0.211 (0.622)	.351	.013
SDMT, total score	0.709 (1.440)	0.723 (0.780)	.827	.001
TMT-A, secondsb	-0.781 (2.073)	-0.375 (1.105)	.446	.008
TMT-B, secondsb	0.860 (4.552)	0.088 (2.364)	.172	.027
Stroop colour	-0.325 (1.478)	0.027 (0.985)	.125	.034
Stroop word	0.112 (1.730)	-0.369 (1.409)	.300	.016
Stroop interference	-0.077 (1.201)	0.071 (0.775)	.470	.008
Reaction time simple, millisecondsb	6.706 (11.411)	4.229 (7.995)	.627	.004
Reaction time complex, millisecondsb	7.893 (8.229)	8.953 (12.164)	.796	.001