Table 1.
Demographic and clinical characteristics at baseline by fatigue status
| Total | Fatigue status |
p Value | |||
|---|---|---|---|---|---|
| Non-fatigued | Fatigued | ||||
| Age (years) |
N Median (IQR) |
128 45 (41.5, 52) |
46 48 (43, 54) |
82 44 (41, 50) |
0.011a |
| Education (years) |
N Median (IQR) |
128 13 (12,16) |
46 12 (11, 15) |
82 14 (12, 16) |
0.053a |
| Gender, N (%N) | Male Female |
112 (88%) 16 (13%) |
41 (89%) 5 (11%) |
71 (87%) 11 (13%) |
0.785b |
| Race/ethnicity, N (%N) |
White Non-Hispanic Black Non-Hispanic |
65 (51%) 46 (36%) |
19 (41%) 19 (41%) |
46 (56%) 27 (33%) |
0.264c |
| Other | 17 (13%) | 8 (17%) | 9(11%) | ||
| MSK stage, N (%N) |
Equivocal/ subclinical Mild |
44 (34%) 71 (55%) |
19 (41%) 25 (54%) |
25 (30%) 46 (56%) |
0.103d |
| Moderate | 13 (10%) | 2 (4%) | 11 (13%) | ||
| FSS score |
N Median (IQR) |
128 4.67 (3.44, 5.78) |
46 2.78 (2.33, 3.56) |
82 5.44 (4.75, 6.22) |
<0.001a |
| CD4+ count (mm3) |
N Median (IQR) |
120 425.5 (261.5, 691.5) |
44 443.5 (268,649) |
76 419 (225, 729) |
0.963a |
| Plasma HIV RNA (copies/ml), N (%N) |
>50 ≤50 |
54 (43%) 73 (57%) |
19 (41%) 27 (59%) |
35 (43%) 46 (57%) |
0.854b |
| CSF HIV RNA (copies/ml), N (%N) |
>50 ≤50 |
22 (26%) 63 (74%) |
12 (34%) 23 (66%) |
10 (20%) 40 (80%) |
0.208b |
| ART usage | N (%) | 122 (95) | 42 (91) | 80 (98) | 0.187b |
| NRTI usage | N (%) | 118 (92) | 41(89) | 77 (94) | 0.494d |
| CES-D scale score |
N Median (IQR) |
127 19 (12, 29) |
46 14.5 (7, 22) |
81 24 (17, 34) |
<0.001a |
| Karnofsky scale score |
N Median (IQR) |
127 80 (80,90) |
45 90 (80, 90) |
82 80 (80,90) |
0.032a |
| NPZ-8 |
N Median (IQR) |
128 −0.95 (−1.55, −0.51) |
46 −0.92 (−1.46, −0.48) |
82 −0.96 (−1.57, −0.52) |
0.704a |
a
Kruskal–Wallis test
b
Fisher’s Exact test
c
Exact Test for R×C Tables
d
Score Test for Ordinal Categorical Data