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. Author manuscript; available in PMC: 2012 Nov 11.
Published in final edited form as: Radiother Oncol. 2011 Nov 11;101(2):329–336. doi: 10.1016/j.radonc.2011.10.020

Figure 4. Masson Trichome staining of fibrosis in A549 lung tumor-bearing mice treated with radiation and soy.

Figure 4

A. Lung tissue from control untreated mice showing typical blue staining of collagen lining surrounding the basement membrane of vessels and bronchioles (arrows) but no staining in lung alveoli. B. Tumor nodule from control untreated mice showing blue peripheral staining of vessels. C, D. Lung tissue from soy treated mice with no significant collagen staining. E, F. Lung tissue from irradiated left lung showing extensive fibrotic tissue staining and hemorrhages (F). G, H. Lung tissue from irradiated left lung of mice treated with left lung irradiation and systemic soy showing lung morphology and limited or no staining of fibrotic tissue and remaining degenerative large tumor cells [arrowheads] with inflammatory infiltrates (H). All magnifications 40X.