Table 2.
Inflammatory Infiltrates | Hemorrhages | Fibrosis | ||||
---|---|---|---|---|---|---|
RL | LL | RL | LL | RL | LL | |
Control | ± | ± | ± | ± | ± | ± |
Radiation | ± | +++ | ± | +++ | ± | ++ |
Soy isoflavones | ± | ± | ± | ± | ± | ± |
Rad + Soy | ± | ± | ± | ± | ± | ± |
Histological findings of normal lung tissue surrounding the tumor nodules, from the experiment presented in Figures 3 and 4 were quantified and the extent of inflammatory infiltrates, hemorrhages and fibrosis were scaled from weak (±), moderate (+), strong (++) to heavy (+++). The fibrotic score was obtained from analysis of lung sections stained with Masson-Trichome as shown in Figure 4. Lung tissue sections of the left and right lung were separately analyzed because only the left lung was irradiated.