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. 2010 Jun 1;92(7):562–568. doi: 10.1308/003588410X12699663903476

Table 2.

Treatment characteristics and clinical outcomes of patients who had breast conservation surgery

Variables (n = 563)
Treatment characteristics
 Re-excision (no. of operations)
  0 502 (89.2%)
  1 60 (10.7%)
  2 1 (0.2%)
 Margin achieved
  < 1 mm 8(1.4%)
  1–2 mm 22 (3.9%)
  3–4 mm 67(11.9%)
 ≥ 5 mm 461 (81.9%)
  Unknown 5 (0.9%)
 Radiation boost
  Yes 340 (60.4%)
  No 223 (39.6%)
 Chemotherapy
  Yes 114(20.2%)
  No 442 (78.5%)
  Unknown 7(1.2%)
 Hormonal therapy
  Yes 442 (78.5%)
  No 85 (15.1%)
  Unknown 36 (6.4%)
Clinical outcomes
 Follow-up: median (range) 4.8 (0.08–8.3) yrs
 5-year actuarial IBTR rate 1.1%
 5-year crude IBTR rate 0.9% (5 of 563)
 5-year actuarial DDR rate 5.4%
 5-year crude DDR rate 5.2% (29 of 563)
 5-year breast cancer specific survival 95.0%
 5-year breast cancer specific survival by NPI groups
  Group 1 (excellent prognostic group) 100%
  Group 2 (good) 99.2%
  Group 3 (moderate I) 96.1%
  Group 4 (moderate II) 86.6%
  Group 5 (poor) 88.6%
  Group 6 (very poor) 75.2%
 Overall 5-year survival 90.3%

IBTR, ipsilateral breast tumour recurrence; DDR, distant disease recurrence; NPI, Nottingham Prognostic Index.