Table 1.
Smooth muscle tumours with usual differentiation | |
Leiomyoma | MI <20 mf/10 hpf |
Leiomyoma with increased mitotic index | No coagulative necrosis |
No atypia or no more than mild cytologic atypia | |
Leiomyoma with increased mitotic index but experience limited | MI >/=20 mf/10 hpf |
No coagulative necrosis | |
No atypia or no more than mild cytologic atypia | |
Atypical leiomyoma with low risk of recurrence | MI<10 mf/10 hpf |
No coagulative necrosis | |
Diffuse moderate to severe cytologic atypia (1/46 failed) | |
Leiomyoma with atypia but limited experience | MI</=10 mf/10 hpf |
No coagulative necrosis | |
Focal moderate to severe cytologic atypia | |
Leiomyosarcoma | Any MI |
Any degree of cytologic atypia with coagulative necrosis (29/39 failed) | |
Usually there will be significant cytolgic atypia | |
Leiomyosarcoma | MI>/=10 mf/10 hpf |
No coagulative necrosis but with diffuse moderate to severe cytologic atypia (4/10 failed) | |
Smooth muscle tumours with myxoid stroma | |
Epithelioid leiomyoma | MI<5 mf/10 hpf |
No coagulative necrosis | |
No atypia or no more than mild cytologic atypia | |
Epithelioid leiomyosarcoma | MI>/=5 mf/10 hpf |
No coagulative necrosis | |
None or any degree of cytologic atypia | |
Or Any MI | |
Any degree of cytologic atypia with coagulative necrosis |
MI, mitotic index.