Table 3.

Proliferation of PDGFRα, PDGFRβ, and IBA-1 expressing cells in wild type and NG2 null mice.

	WT	KO
Total Pα positive cells	178.23 ± 20.3	127.94 ± 18.4*
Pα/BrdU positive cells	26.4 ± 2.2	10.76 ± 2.9
Mitotic indices	14.81 ± 3.1%	8.41 ± 0.6%**
Total Pβ positive cells	29.8 ± 5.7	21.91 ± 3.4*
Pβ/BrdU positive cells	4.53 ± 0.8	2.31 ± 0.9
Mitotic indices	15.2 ± 0.6%	10.52 ± 0.6%***
Total IBA-1 positive cells	217.94 ± 14.8	74.45 ± 12.3***
IBA1/BrdU positive cells	19.66 ± 3.6	4.71 ± 3.5
Mitotic indices	9.02 ± 1.2%	6.32 ± 1.8%*

Total numbers of PDGFRα (Pα), PDGFRβ (Pβ), and IBA-1 positive cells, along with BrdU incorporation, were determined in 0.1 mm² areas of the dorsal column at 7 days postsurgery. Mitotic labeling indices for OPCs, pericytes, and macrophages/microglial cells are expressed as the percentage of each cell type that is BrdU positive. Data represent the mean ± S.D. Statistically significant differences between wild type and NG2 null mice are indicated by * < 0.05; ** < 0.01; *** < 0.001.