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. 2011 Oct 21;10:187. doi: 10.1186/1476-511X-10-187

Figure 4.

Figure 4

Simulated reduction (%) in LDL cholesterol after treatment with different doses of phytosterols/-stanols. The solid line shows the fit to the model and symbols represent experimental data from Demonty et al. [22] Values for the Michaelis-Menten parameters are: effective maximum LDL cholesterol reduction (RU, max) = 0.221 and half maximum reduction phytosterol/-stanol dose (PSU, 1/2) = 1.78 mg/d. The dashed lines show the 5% and 95% uncertainty range in reduction obtained by correlated sampling (correlation coefficient ρ = 0.98) of RU, max and PSU, 1/2 from their covariance matrix.