Table 1. Individual association of 6 genotyped SNPs in the empirical study.

			Controls		Cases
Gene	Variant	Risk Allele	n genotyped	RAF	n genotyped	RAF	OR (95% CI)	p-value
HLA-DRB	rs3135388	T	599	0.14	588	0.28	2.53 (2.02–3.17)	8.14*10−16
EVI5	rs10735781	G	597	0.33	586	0.38	1.19 (1.01–1.42)	0.044
CLEC16A	rs64981169	G	593	0.33	583	0.39	1.27 (1.07–1.51)	0.006
CD58	rs12044852	C	599	0.88	587	0.91	1.50 (1.14–1.97)	0.004
IL7R	rs6897932	C	599	0.72	588	0.76	1.21 (1.00–1.46)	0.045
IL2RA	rs2104286	A	595	0.73	581	0.76	1.14 (0.95–1.38)	0.157

RAF: risk allele frequency, OR: odds ratio, 95% CI: 95% confidence interval.