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. 2011 Dec 2;6(12):e28102. doi: 10.1371/journal.pone.0028102

Table 3. Sensitivity and specificity of symptom and sign combinations for the identification of 2009 influenza A virus (H1N1) infection.

Symptoms and signs non-influenza illness vs.2009 influenza A virus (H1N1) infection
children adults
Sensitivity (%) Specificity (%) Sensitivity (%) Specificity (%)
Single symptom or sign Fever 99 6 88 23
Cough 95 20 85 46
Coryza 71 34 33 67
Sore throat 58 82 65 54
Any respiratory symptom 98 13 96 24
Headache 43 85 23 81
Malaise 23 94 30 80
Myalgia 59 80 61 52
Any constitutional symptom 78 69 83 40
Symptom and sign combinations Fever + cough 94 23 74 59
Any respiratory + any constitutional symptom 77 74 79 56
Fever + any respiratory symptom 97 17 84 43
Fever + any constitutional symptom 77 73 76 53
Cough + any constitutional symptom 74 78 70 71
Influenza-like illness 76 77 72 65
Rapid influenza diagnostic test 57 100 38 100