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. 2011 Dec 2;6(12):e28435. doi: 10.1371/journal.pone.0028435

Table 4. PCV-7 vaccine effectiveness estimates.

Age of IPD cases Doses for VE estimate VT casesvaccinated / totala (%) NVT casesvaccinated / totala (%) Crude VE(95% CI) Adjusted b VE (95% CI)
<14 months 1 dose routine/older infants 17/35 (49%)c 59/87 (68%) 55% (1–80) 56% (-7–82)
2 dose routine 18/23 (78%) 265/282 (94%) 77% (30–92) 79% (24–94)
2 dose routine/older infants 20/38 (53%) 275/303 (91%) 89% (76–95) 83% (60–93)
≥14 months 2 dose routine + booster 7/8 (88%) 199/209 (95%) 65% (-214–96) 62% (-315–96)
2 dose routine/older infants + booster 7/15 (47%) 243/260 (93%) 94% (81–98) 93% (70–98)
1 dose catch-up 21/74 (28%) 141/190 (74%) 86% (75–92) 78% (56–89)
a

This is the total either unvaccinated or with the stated schedule.

b

Adjusted for age, gender and period.

c

17/35 comes from Table 3 as (10+7)/(10+7+5+13) where 10 and 7 are the one partial dose for routine/older infants and 5 and 13 are the unvaccinated for these groups.