Figure 7. Performance of the “sequence features” model on an independent TS mutant set.

A total of 149 TS mutants from 110 yeast genes form the independent testing set. The mutants were grouped based on their restrictive temperatures. The probability of being TS was calculated for each mutant using the “sequence features” model. Average probabilities with standard errors are shown for each group, ranging in size from n = 6 to n = 31.