Table 2.

Statistics of putative genes involved in camptothecin biosynthesis^a

Enzyme code	Name of enzyme	Number of unigenes in cDNA library	Number of ESTs in cDNA library	Number of nucleotides in GenBank
2.3.1.9	acetoacetyl-CoA thiolase	2	15	0
2.3.3.10	HMG-CoA synthase	4	7	1
1.1.1.34	HMG-CoA reductase	2	9	3
2.7.1.36	mevalonate kinase	1	5	0
2.7.4.2	phosphomevalonate kinase	2	2	0
4.1.1.33	mevalonate-5-diphosphate decarboxylase	2	6	0
2.2.1.7	DXP synthase	8	105	0
1.1.1.267	DXP reductoisomerase	1	19	1
2.7.7.60	MEP cytidylyltransferase	0	0	0
2.7.1.148	CDP-ME kinase	3	3	0
4.6.1.12	MECDP synthase	1	1	0
1.17.7.1	4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	1	33	0
1.17.1.2	4-hydroxy-3-methylbut-2-enyl-diphosphate reductase	1	13	0
5.3.3.2	isopentenyl-PP isomerase	2	11	1
2.5.1.10	farnesyl diphosphate synthase	4	13	0
1.14.14.1	geraniol 10-hydroxylase	1	11	0
1.-.-.-	10-HG oxidoreductase	3	84	1
1.3.3.9	secologanin synthase	17	165	0
4.2.1.20	β-subunit of tryptophan synthase	4	4	2
4.1.1.28	tryptophan decarboxylase	1	1	2
4.3.3.2	strictosidine synthase	6	14	0
Total number		66	521	11

Notes: ^a--Total numbers when annotated against Nr, Swissprot and Kegg databases.