Table 5.
Depletion kinetics 4-OH-RA, 4-oxo-RA and 18-OH-RA by CYP26A1 and CYP26B1.
| RA Metabolite | CYP26A1 | CYP26B1 |
|---|---|---|
| kdep (min−1) | ||
| 4-OH-RA | 0.10 ± 0.01 | 0.03 ± 0.01 |
| 18-OH-RA | 0.12 ± 0.01 | 0.03 ± 0.01 |
| 4-oxo-RA | 0.05 ± 0.01 | 0.02 ± 0.00 |
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