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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Clin Cancer Res. 2011 Sep 8;17(23):7359–7372. doi: 10.1158/1078-0432.CCR-11-1388

Figure 6. Akt inhibition in murine and human ovarian tumor cells results in compensatory activation of MEK/ERK signaling.

Figure 6

Immunoblots of lysates from A) W2671T and W2830T and B) A2780 cells treated for 2 hr with varying doses of perifosine; C) W2671T and W2830T and D) A2780-S33Y and A2780-Neo cells treated with 40 μM API-2 over the indicated time course; E) W2830T cells treated with 100nM rapamycin for up to 24 hr. In each blot, levels of phosphorylated and total Akt, ERK, and S6 are shown.